Current knowledge about and recommendations for ocular methicillin-resistant Staphylococcus aureus.

Journal Article (Journal Article;Review)

UNLABELLED: Staphylococcus aureus is the most important and common pathogen that infects patients following cataract surgery, laser in situ keratomileusis, and photorefractive keratectomy. It is reported to be the second most common pathogen causing bacterial keratitis around the world. Of special concern are increasing reports of postoperative methicillin-resistant S aureus (MRSA) infection. For example, MRSA wound infections have been reported with clear corneal phacoemulsification wounds, penetrating keratoplasty, lamellar keratoplasty, and following ex vivo epithelial transplantation associated with amniotic membrane grafts. These and other data suggest that MRSA has become increasingly prevalent worldwide. In this article, we review the current medical literature and describe the current challenge of ocular MRSA infections. Recommendations are made based on an evidence-based review to identify, treat, and possibly reduce the overall problem of this organism. FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.

Full Text

Duke Authors

Cited Authors

  • Mah, FS; Davidson, R; Holland, EJ; Hovanesian, J; John, T; Kanellopoulos, J; Shamie, N; Starr, C; Vroman, D; Kim, T; ASCRS Cornea Clinical Committee,

Published Date

  • November 2014

Published In

Volume / Issue

  • 40 / 11

Start / End Page

  • 1894 - 1908

PubMed ID

  • 25442885

Electronic International Standard Serial Number (EISSN)

  • 1873-4502

Digital Object Identifier (DOI)

  • 10.1016/j.jcrs.2014.09.023


  • eng

Conference Location

  • United States