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A precisely defined role for the tip link-associated protein TMIE in the mechanoelectrical transduction channel complex of inner ear hair cells.

Publication ,  Journal Article
Liedtke, W
Published in: Neuron
December 3, 2014

Inner ear hair cells transduce sound waves and acceleration. In the quest to identify the molecular machinery underlying mechanoelectrical transduction, Zhao et al. (2014) in this issue of Neuron reveal that the TMIE protein, essential for hearing, physically interacts with tip link protein protocadherin-15.

Duke Scholars

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Published In

Neuron

DOI

EISSN

1097-4199

Publication Date

December 3, 2014

Volume

84

Issue

5

Start / End Page

889 / 891

Location

United States

Related Subject Headings

  • Protein Precursors
  • Neurology & Neurosurgery
  • Membrane Proteins
  • Mechanotransduction, Cellular
  • Humans
  • Hair Cells, Auditory
  • Cadherins
  • Cadherin Related Proteins
  • Animals
  • 5202 Biological psychology
 
Journal cover image

Published In

Neuron

DOI

EISSN

1097-4199

Publication Date

December 3, 2014

Volume

84

Issue

5

Start / End Page

889 / 891

Location

United States

Related Subject Headings

  • Protein Precursors
  • Neurology & Neurosurgery
  • Membrane Proteins
  • Mechanotransduction, Cellular
  • Humans
  • Hair Cells, Auditory
  • Cadherins
  • Cadherin Related Proteins
  • Animals
  • 5202 Biological psychology