Harnessing the Power of Integrated Mitochondrial Biology and Physiology: A Special Report on the NHLBI Mitochondria in Heart Diseases Initiative.

Journal Article (Journal Article)

Mitochondrial biology is the sum of diverse phenomena from molecular profiles to physiological functions. A mechanistic understanding of mitochondria in disease development, and hence the future prospect of clinical translations, relies on a systems-level integration of expertise from multiple fields of investigation. Upon the successful conclusion of a recent National Institutes of Health, National Heart, Lung, and Blood Institute initiative on integrative mitochondrial biology in cardiovascular diseases, we reflect on the accomplishments made possible by this unique interdisciplinary collaboration effort and exciting new fronts on the study of these remarkable organelles.

Full Text

Duke Authors

Cited Authors

  • Ping, P; Gustafsson, ÅB; Bers, DM; Blatter, LA; Cai, H; Jahangir, A; Kelly, D; Muoio, D; O'Rourke, B; Rabinovitch, P; Trayanova, N; Van Eyk, J; Weiss, JN; Wong, R; Schwartz Longacre, L

Published Date

  • July 17, 2015

Published In

Volume / Issue

  • 117 / 3

Start / End Page

  • 234 - 238

PubMed ID

  • 26185209

Pubmed Central ID

  • PMC4535701

Electronic International Standard Serial Number (EISSN)

  • 1524-4571

Digital Object Identifier (DOI)

  • 10.1161/CIRCRESAHA.117.306693


  • eng

Conference Location

  • United States