Design and implementation of a study evaluating extinction processes to food cues in obese children: the Intervention for Regulations of Cues Trial (iROC).

Journal Article (Clinical Trial;Journal Article)

Obesity and its health sequelae affect a significant portion of children in the United States. Yet, the current gold-standard family-based behavioral weight-loss treatments are only effective for one-third of children long-term. Therefore, we developed iROC (Intervention for Regulation of Cues) to specifically target a method to decrease overeating in overweight children, based on learning theory, to inform and enhance interventions targeting diet and obesity in youth. This study will rigorously test extinction processes as a method of decreasing physiological and psychological responses to food cues in overweight and obese children. Through exposing children to their highly craved foods, and 'training the brain and body' to decrease overeating, we are hoping to produce longer-lasting weight loss or weight-gain prevention over time.

Full Text

Duke Authors

Cited Authors

  • Boutelle, KN; Liang, J; Knatz, S; Matheson, B; Risbrough, V; Strong, D; Rhee, KE; Craske, MG; Zucker, N; Bouton, ME

Published Date

  • January 2015

Published In

Volume / Issue

  • 40 /

Start / End Page

  • 95 - 104

PubMed ID

  • 25461494

Pubmed Central ID

  • PMC4314468

Electronic International Standard Serial Number (EISSN)

  • 1559-2030

Digital Object Identifier (DOI)

  • 10.1016/j.cct.2014.11.011


  • eng

Conference Location

  • United States