Cancer-Related Fatigue, Version 2.2015.

Journal Article (Journal Article)

Cancer-related fatigue is defined as a distressing, persistent, subjective sense of physical, emotional, and/or cognitive tiredness or exhaustion related to cancer or cancer treatment that is not proportional to recent activity and interferes with usual functioning. It is one of the most common side effects in patients with cancer. Fatigue has been shown to be a consequence of active treatment, but it may also persist into posttreatment periods. Furthermore, difficulties in end-of-life care can be compounded by fatigue. The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Cancer-Related Fatigue provide guidance on screening for fatigue and recommendations for interventions based on the stage of treatment. Interventions may include education and counseling, general strategies for the management of fatigue, and specific nonpharmacologic and pharmacologic interventions. Fatigue is a frequently underreported complication in patients with cancer and, when reported, is responsible for reduced quality of life. Therefore, routine screening to identify fatigue is an important component in improving the quality of life for patients living with cancer.

Full Text

Duke Authors

Cited Authors

  • Berger, AM; Mooney, K; Alvarez-Perez, A; Breitbart, WS; Carpenter, KM; Cella, D; Cleeland, C; Dotan, E; Eisenberger, MA; Escalante, CP; Jacobsen, PB; Jankowski, C; LeBlanc, T; Ligibel, JA; Loggers, ET; Mandrell, B; Murphy, BA; Palesh, O; Pirl, WF; Plaxe, SC; Riba, MB; Rugo, HS; Salvador, C; Wagner, LI; Wagner-Johnston, ND; Zachariah, FJ; Bergman, MA; Smith, C; National comprehensive cancer network,

Published Date

  • August 2015

Published In

Volume / Issue

  • 13 / 8

Start / End Page

  • 1012 - 1039

PubMed ID

  • 26285247

Pubmed Central ID

  • PMC5499710

Electronic International Standard Serial Number (EISSN)

  • 1540-1413

Digital Object Identifier (DOI)

  • 10.6004/jnccn.2015.0122


  • eng

Conference Location

  • United States