Inflammatory biomarkers in osteoarthritis.
Published
Journal Article (Review)
Osteoarthritis (OA) is highly prevalent and a leading cause of disability worldwide. Despite the global burden of OA, diagnostic tests and treatments for the molecular or early subclinical stages are still not available for clinical use. In recent years, there has been a large shift in the understanding of OA as a "wear and tear" disease to an inflammatory disease. This has been demonstrated through various studies using MRI, ultrasound, histochemistry, and biomarkers. It would of great value to be able to readily identify subclinical and/or sub-acute inflammation, particularly in such a way as to be appropriate for a clinical setting. Here we review several types of biomarkers associated with OA in human studies that point to a role of inflammation in OA.
Full Text
Duke Authors
Cited Authors
- Daghestani, HN; Kraus, VB
Published Date
- November 2015
Published In
Volume / Issue
- 23 / 11
Start / End Page
- 1890 - 1896
PubMed ID
- 26521734
Pubmed Central ID
- 26521734
Electronic International Standard Serial Number (EISSN)
- 1522-9653
Digital Object Identifier (DOI)
- 10.1016/j.joca.2015.02.009
Language
- eng
Conference Location
- England