Atlas-based automated segmentation of spleen and liver using adaptive enhancement estimation

Published

Conference Paper

The paper presents the automated segmentation of spleen and liver from contrast-enhanced CT images of normal and hepato/splenomegaly populations. The method used 4 steps: (i) a mean organ model was registered to the patient CT; (ii) the first estimates of the organs were improved by a geodesic active contour; (iii) the contrast enhancements of liver and spleen were estimated to adjust to patient image characteristics, and an adaptive convolution refined the segmentations; (iv) lastly, a normalized probabilistic atlas corrected for shape and location for the precise computation of each organ's volume and height (mid-hepatic liver height and cephalocaudal spleen height). Results from test data demonstrated the method's ability to accurately segment the spleen (RMS error = 1.09mm; DICE/Tanimoto overlaps = 95.2/91) and liver (RMS error = 2.3mm, and DICE/Tanimoto overlaps = 96.2/92.7). The correlations (R2) with clinical/manual height measurements were 0.97 and 0.93 for the spleen and liver respectively. © 2009 Springer-Verlag.

Full Text

Duke Authors

Cited Authors

  • Linguraru, MG; Sandberg, JK; Li, Z; Pura, JA; Summers, RM

Published Date

  • December 1, 2009

Published In

Volume / Issue

  • 5762 LNCS / PART 2

Start / End Page

  • 1001 - 1008

Electronic International Standard Serial Number (EISSN)

  • 1611-3349

International Standard Serial Number (ISSN)

  • 0302-9743

International Standard Book Number 10 (ISBN-10)

  • 3642042708

International Standard Book Number 13 (ISBN-13)

  • 9783642042706

Digital Object Identifier (DOI)

  • 10.1007/978-3-642-04271-3_121

Citation Source

  • Scopus