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The macrophage: Switches from a passenger to a driver during anticancer therapy.

Publication ,  Journal Article
Wang, T; Feldman, GM; Herlyn, M; Kaufman, RE
Published in: Oncoimmunology
December 2015

We have recently discovered that BRAF inhibitors induce potent macrophage responses that confer melanoma resistance to therapy. Our studies lay a foundation for the hypothesis that macrophages switch their role from a passenger to a driver for tumor survival during therapeutic treatment, suggesting that agents that target macrophages can be an important component of "cocktail" anticancer therapy.

Duke Scholars

Published In

Oncoimmunology

DOI

ISSN

2162-4011

Publication Date

December 2015

Volume

4

Issue

12

Start / End Page

e1052929

Location

United States

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 3204 Immunology
  • 1112 Oncology and Carcinogenesis
  • 1107 Immunology
 

Citation

APA
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ICMJE
MLA
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Wang, T., Feldman, G. M., Herlyn, M., & Kaufman, R. E. (2015). The macrophage: Switches from a passenger to a driver during anticancer therapy. Oncoimmunology, 4(12), e1052929. https://doi.org/10.1080/2162402X.2015.1052929
Wang, Tao, Gerald M. Feldman, Meenhard Herlyn, and Russel E. Kaufman. “The macrophage: Switches from a passenger to a driver during anticancer therapy.Oncoimmunology 4, no. 12 (December 2015): e1052929. https://doi.org/10.1080/2162402X.2015.1052929.
Wang T, Feldman GM, Herlyn M, Kaufman RE. The macrophage: Switches from a passenger to a driver during anticancer therapy. Oncoimmunology. 2015 Dec;4(12):e1052929.
Wang, Tao, et al. “The macrophage: Switches from a passenger to a driver during anticancer therapy.Oncoimmunology, vol. 4, no. 12, Dec. 2015, p. e1052929. Pubmed, doi:10.1080/2162402X.2015.1052929.
Wang T, Feldman GM, Herlyn M, Kaufman RE. The macrophage: Switches from a passenger to a driver during anticancer therapy. Oncoimmunology. 2015 Dec;4(12):e1052929.

Published In

Oncoimmunology

DOI

ISSN

2162-4011

Publication Date

December 2015

Volume

4

Issue

12

Start / End Page

e1052929

Location

United States

Related Subject Headings

  • 3211 Oncology and carcinogenesis
  • 3204 Immunology
  • 1112 Oncology and Carcinogenesis
  • 1107 Immunology