Advances in enzymology and related areas of molecular biology


Natural products continue to play an important role in the treatment of human disease. Among the most daunting limitations to the use of such species is the need for synthetic approaches to the significant quantities of material needed for biochemical study, preclinical and clinical evaluation and, ultimately, supply. Although synthetic chemistry has made tremendous advances in enantiopure synthesis, material limitations still loom large in the development of natural product therapeutics.

Full Text

Duke Authors

Cited Authors

  • Toone, EJ

Published Date

  • September 29, 2008

Volume / Issue

  • 76 /

Start / End Page

  • 1 - 272

International Standard Book Number 13 (ISBN-13)

  • 9780471235842

Digital Object Identifier (DOI)

  • 10.1002/9780470392881

Citation Source

  • Scopus