Skip to main content
Journal cover image

Construction and validation of the chronic acquired polyneuropathy patient-reported index (CAP-PRI): A disease-specific, health-related quality-of-life instrument.

Publication ,  Journal Article
Gwathmey, KG; Conaway, MR; Sadjadi, R; Joshi, A; Barnett, C; Bril, V; Ng, E; David, W; Gable, K; Guptill, JT; Hobson-Webb, LD; Dineen, J ...
Published in: Muscle Nerve
June 2016

INTRODUCTION: Generic health-related quality-of-life (HRQOL) patient-reported outcome measures have been used in patients with chronic immune-mediated polyneuropathies. We have created a disease-specific HRQOL instrument. METHODS: The chronic acquired polyneuropathy patient-reported index (CAP-PRI) was developed and validated in multiple steps. Items were initially generated through patient and specialist input. The performance of the preliminary 20 items was analyzed via a prospective, 5-center study involving chronic immune-mediated polyneuropathy patients. RESULTS: Data analysis suggested modification to a 15-item scale with 3 response categories rather than 5. The final CAP-PRI was validated in another prospective, 5-center study. The CAP-PRI appeared to be a unidimensional outcome measure that fit the Rasch model in our multicenter cohort. It correlated appropriately with outcome measures commonly used in this patient population. CONCLUSIONS: The CAP-PRI is a simple disease-specific HRQOL measure that appears to be useful for clinical care and possibly also for clinical trials. Muscle Nerve 54: 9-17, 2016.

Duke Scholars

Published In

Muscle Nerve

DOI

EISSN

1097-4598

Publication Date

June 2016

Volume

54

Issue

1

Start / End Page

9 / 17

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Statistics, Nonparametric
  • Retrospective Studies
  • Reproducibility of Results
  • Quality of Life
  • Psychometrics
  • Prospective Studies
  • Polyneuropathies
  • Neurology & Neurosurgery
  • Male
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Gwathmey, K. G., Conaway, M. R., Sadjadi, R., Joshi, A., Barnett, C., Bril, V., … Burns, T. M. (2016). Construction and validation of the chronic acquired polyneuropathy patient-reported index (CAP-PRI): A disease-specific, health-related quality-of-life instrument. Muscle Nerve, 54(1), 9–17. https://doi.org/10.1002/mus.24985
Gwathmey, Kelly G., Mark R. Conaway, Reza Sadjadi, Amruta Joshi, Carolina Barnett, Vera Bril, Eduardo Ng, et al. “Construction and validation of the chronic acquired polyneuropathy patient-reported index (CAP-PRI): A disease-specific, health-related quality-of-life instrument.Muscle Nerve 54, no. 1 (June 2016): 9–17. https://doi.org/10.1002/mus.24985.
Gwathmey, Kelly G., et al. “Construction and validation of the chronic acquired polyneuropathy patient-reported index (CAP-PRI): A disease-specific, health-related quality-of-life instrument.Muscle Nerve, vol. 54, no. 1, June 2016, pp. 9–17. Pubmed, doi:10.1002/mus.24985.
Gwathmey KG, Conaway MR, Sadjadi R, Joshi A, Barnett C, Bril V, Ng E, David W, Gable K, Guptill JT, Hobson-Webb LD, Dineen J, Hehir M, Brannagan TH, Byun E, Adler M, Burns TM. Construction and validation of the chronic acquired polyneuropathy patient-reported index (CAP-PRI): A disease-specific, health-related quality-of-life instrument. Muscle Nerve. 2016 Jun;54(1):9–17.
Journal cover image

Published In

Muscle Nerve

DOI

EISSN

1097-4598

Publication Date

June 2016

Volume

54

Issue

1

Start / End Page

9 / 17

Location

United States

Related Subject Headings

  • Surveys and Questionnaires
  • Statistics, Nonparametric
  • Retrospective Studies
  • Reproducibility of Results
  • Quality of Life
  • Psychometrics
  • Prospective Studies
  • Polyneuropathies
  • Neurology & Neurosurgery
  • Male