Combinatorial Biomolecular Nanopatterning for High-Throughput Screening of Stem-Cell Behavior.


Journal Article

A novel combinatorial biomolecular nanopatterning method is reported, in which multiple biomolecular ligands can be patterned in multiple nanoscale dimensions on a single surface. The applicability of the combinatorial platform toward cell-biology applications is demonstrated by screening the adhesion behavior of a population of human dental pulp stem cell (hDPSC) on 64 combinations of nanopatterned extracellular matrix (ECM) proteins in parallel.

Full Text

Cited Authors

  • Amin, YYI; Runager, K; Simoes, F; Celiz, A; Taresco, V; Rossi, R; Enghild, JJ; Abildtrup, LA; Kraft, DCE; Sutherland, DS; Alexander, MR; Foss, M; Ogaki, R

Published Date

  • February 2016

Published In

Volume / Issue

  • 28 / 7

Start / End Page

  • 1472 - 1476

PubMed ID

  • 26650176

Pubmed Central ID

  • 26650176

Electronic International Standard Serial Number (EISSN)

  • 1521-4095

International Standard Serial Number (ISSN)

  • 0935-9648

Digital Object Identifier (DOI)

  • 10.1002/adma.201504995


  • eng