Avoiding Cardiovascular Collapse: Pediatric Cutaneous Mastocytosis and Anesthetic Challenges.
Journal Article (Journal Article)
Mastocytosis includes a spectrum of diseases characterized by abnormal mast cell infiltration in various organs, which can lead to mast cell mediator release and immediate hypersensitivity. We review anesthetic challenges presented by a 6-year-old girl with a history of mast cell mediator release because of the urticaria pigmentosa variant of cutaneous mastocytosis, factor VII deficiency, increasing episodes of urinary tract infections, and pyelonephritis. She underwent spine magnetic resonance imaging, subsequent lumbar laminectomy for fatty filum release, and a cystourethroscopy. Perioperative management included factor VII desensitization, avoidance of triggers, minimizing histamine-releasing medications, mast cell stabilization, and preparation for potential immediate hypersensitivity.
Full Text
Duke Authors
Cited Authors
- Tew, S; Taicher, BM
Published Date
- November 15, 2015
Published In
Volume / Issue
- 5 / 10
Start / End Page
- 179 - 181
PubMed ID
- 26576050
Electronic International Standard Serial Number (EISSN)
- 2325-7237
Digital Object Identifier (DOI)
- 10.1213/XAA.0000000000000227
Language
- eng
Conference Location
- United States