Natural history of comorbid orofacial pain among women with vestibulodynia.


Journal Article

OBJECTIVES: We evaluated the stability of the comorbidity between vulvodynia and orofacial pain (OFP) and its associated clinical characteristics over a 2-year follow-up period. MATERIALS AND METHODS: In an earlier study of vestibulodynia patients, we administered questionnaires assessing demographic data, self-reported pain, anxiety, somatic awareness, and presence of signs and symptoms suggestive of clinical and subclinical OFP. The present study readministered the same surveys to a subset of the original cohort after a 2-year follow-up period. RESULTS: Of the 138 women in the previous study, 71 (51%) agreed to participate in the present study. We confirmed our earlier findings that (1) OFP is a highly prevalent (66%) condition among women with vestibulodynia, and (2) compared with women with no OFP symptoms, those with OFP symptoms experience higher levels of anxiety (P=0.005) and somatic awareness (P<0.001). Although OFP symptoms showed improvement in many of the vestibulodynia patients (33%) with OFP symptoms at baseline, 13% had either developed new symptoms or transitioned from subclinical to clinical OFP classification. Intercourse-related pain decreased in 69% of patients and increased in 24% of patients. Consistent with our earlier report, we did not observe significant differences with respect to demographics or severity of pain during intercourse among the subgroups. DISCUSSION: OFP is a common comorbidity among women with vestibulodynia, although the presence of OFP can vary over time. The comorbidity between vestibulodynia and OFP suggests that common underlying mechanisms may mediate both conditions.

Full Text

Duke Authors

Cited Authors

  • Bair, E; Simmons, E; Hartung, J; Desia, K; Maixner, W; Zolnoun, D

Published Date

  • January 2015

Published In

Volume / Issue

  • 31 / 1

Start / End Page

  • 73 - 78

PubMed ID

  • 24566384

Pubmed Central ID

  • 24566384

Electronic International Standard Serial Number (EISSN)

  • 1536-5409

Digital Object Identifier (DOI)

  • 10.1097/AJP.0000000000000087


  • eng

Conference Location

  • United States