A physical map of 30,000 human genes.

Journal Article

A map of 30,181 human gene-based markers was assembled and integrated with the current genetic map by radiation hybrid mapping. The new gene map contains nearly twice as many genes as the previous release, includes most genes that encode proteins of known function, and is twofold to threefold more accurate than the previous version. A redesigned, more informative and functional World Wide Web site (www.ncbi.nlm.nih.gov/genemap) provides the mapping information and associated data and annotations. This resource constitutes an important infrastructure and tool for the study of complex genetic traits, the positional cloning of disease genes, the cross-referencing of mammalian genomes, and validated human transcribed sequences for large-scale studies of gene expression.

Full Text

Duke Authors

Cited Authors

  • Deloukas, P; Schuler, GD; Gyapay, G; Beasley, EM; Soderlund, C; Rodriguez-Tomé, P; Hui, L; Matise, TC; McKusick, KB; Beckmann, JS; Bentolila, S; Bihoreau, M; Birren, BB; Browne, J; Butler, A; Castle, AB; Chiannilkulchai, N; Clee, C; Day, PJ; Dehejia, A; Dibling, T; Drouot, N; Duprat, S; Fizames, C; Fox, S; Gelling, S; Green, L; Harrison, P; Hocking, R; Holloway, E; Hunt, S; Keil, S; Lijnzaad, P; Louis-Dit-Sully, C; Ma, J; Mendis, A; Miller, J; Morissette, J; Muselet, D; Nusbaum, HC; Peck, A et al.

Published Date

  • October 1998

Published In

Volume / Issue

  • 282 / 5389

Start / End Page

  • 744 - 746

PubMed ID

  • 9784132

Electronic International Standard Serial Number (EISSN)

  • 1095-9203

International Standard Serial Number (ISSN)

  • 0036-8075

Digital Object Identifier (DOI)

  • 10.1126/science.282.5389.744

Language

  • eng