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Resting state cortical connectivity reflected in EEG coherence in individuals with autism.

Publication ,  Journal Article
Murias, M; Webb, SJ; Greenson, J; Dawson, G
Published in: Biol Psychiatry
August 1, 2007

BACKGROUND: Theoretical conceptions of autism spectrum disorder (ASD) and experimental studies of cerebral blood flow suggest abnormalities in connections among distributed neural systems in ASD. METHODS: Functional connectivity was assessed with electroencephalographic coherence between pairs of electrodes in a high-density electrode array in narrow frequency bands among 18 adults with ASD and 18 control adults in an eyes closed resting state. RESULTS: In the theta (3-6 Hz) frequency range, locally elevated coherence was evident for the ASD group, especially within left hemisphere frontal and temporal regions. In the lower alpha range (8-10 Hz), globally reduced coherence was evident for the ASD group within frontal regions and between frontal and all other scalp regions. The ASD group exhibited significantly greater relative power between 3 and 6 Hz and 13-17 Hz and significantly less relative power between 9 and 10 Hz. CONCLUSIONS: Robust patterns of over- and under-connectivity are apparent at distinct spatial and temporal scales in ASD subjects in the eyes closed resting state.

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Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

August 1, 2007

Volume

62

Issue

3

Start / End Page

270 / 273

Location

United States

Related Subject Headings

  • Reference Values
  • Psychiatry
  • Neural Pathways
  • Male
  • Humans
  • Electroencephalography
  • Cortical Synchronization
  • Cerebral Cortex
  • Case-Control Studies
  • Brain Mapping
 

Citation

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Murias, M., Webb, S. J., Greenson, J., & Dawson, G. (2007). Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Biol Psychiatry, 62(3), 270–273. https://doi.org/10.1016/j.biopsych.2006.11.012
Murias, Michael, Sara J. Webb, Jessica Greenson, and Geraldine Dawson. “Resting state cortical connectivity reflected in EEG coherence in individuals with autism.Biol Psychiatry 62, no. 3 (August 1, 2007): 270–73. https://doi.org/10.1016/j.biopsych.2006.11.012.
Murias M, Webb SJ, Greenson J, Dawson G. Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Biol Psychiatry. 2007 Aug 1;62(3):270–3.
Murias, Michael, et al. “Resting state cortical connectivity reflected in EEG coherence in individuals with autism.Biol Psychiatry, vol. 62, no. 3, Aug. 2007, pp. 270–73. Pubmed, doi:10.1016/j.biopsych.2006.11.012.
Murias M, Webb SJ, Greenson J, Dawson G. Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Biol Psychiatry. 2007 Aug 1;62(3):270–273.
Journal cover image

Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

August 1, 2007

Volume

62

Issue

3

Start / End Page

270 / 273

Location

United States

Related Subject Headings

  • Reference Values
  • Psychiatry
  • Neural Pathways
  • Male
  • Humans
  • Electroencephalography
  • Cortical Synchronization
  • Cerebral Cortex
  • Case-Control Studies
  • Brain Mapping