Clinical equipoise and personal equipoise: Two necessary ingredients for reducing bias in manual therapy trials


Journal Article (Review)

Clinical and personal equipoise exists when a clinician has no good basis for a choice between two or more care options or when one is truly uncertain about the overall benefit or harm offered by the treatment to his/her patient. For most manual therapy trials, equipoise does not likely exist. Because of the nature of the intervention a lack of equipoise can lead to bias and may account for a portion of the 'effect' that has traditionally been assigned to the intervention. Although there are methodological mechanisms to reduce the risk of bias associated with a lack of equipoise, most of the manual therapy trials to date are likely guilty of this form of bias. © W. S. Maney & Son Ltd 2011.

Full Text

Duke Authors

Cited Authors

  • Cook, C; Sheets, C

Published Date

  • March 14, 2011

Published In

Volume / Issue

  • 19 / 1

Start / End Page

  • 55 - 57

Electronic International Standard Serial Number (EISSN)

  • 2042-6186

International Standard Serial Number (ISSN)

  • 1066-9817

Digital Object Identifier (DOI)

  • 10.1179/106698111X12899036752014

Citation Source

  • Scopus