ZDOCK and RDOCK performance in CAPRI rounds 3, 4, and 5.
Journal Article (Journal Article)
We present an evaluation of the results of our ZDOCK and RDOCK algorithms in Rounds 3, 4, and 5 of the protein docking challenge CAPRI. ZDOCK is a Fast Fourier Transform (FFT)-based, initial-stage rigid-body docking algorithm, and RDOCK is an energy minimization algorithm for refining and reranking ZDOCK results. Of the 9 targets for which we submitted predictions, we attained at least acceptable accuracy for 7, at least medium accuracy for 6, and high accuracy for 3. These results are evidence that ZDOCK in combination with RDOCK is capable of making accurate predictions on a diverse set of protein complexes.
Full Text
Duke Authors
Cited Authors
- Wiehe, K; Pierce, B; Mintseris, J; Tong, WW; Anderson, R; Chen, R; Weng, Z
Published Date
- August 1, 2005
Published In
Volume / Issue
- 60 / 2
Start / End Page
- 207 - 213
PubMed ID
- 15981263
Electronic International Standard Serial Number (EISSN)
- 1097-0134
Digital Object Identifier (DOI)
- 10.1002/prot.20559
Language
- eng
Conference Location
- United States