ZDOCK and RDOCK performance in CAPRI rounds 3, 4, and 5.

Journal Article (Journal Article)

We present an evaluation of the results of our ZDOCK and RDOCK algorithms in Rounds 3, 4, and 5 of the protein docking challenge CAPRI. ZDOCK is a Fast Fourier Transform (FFT)-based, initial-stage rigid-body docking algorithm, and RDOCK is an energy minimization algorithm for refining and reranking ZDOCK results. Of the 9 targets for which we submitted predictions, we attained at least acceptable accuracy for 7, at least medium accuracy for 6, and high accuracy for 3. These results are evidence that ZDOCK in combination with RDOCK is capable of making accurate predictions on a diverse set of protein complexes.

Full Text

Duke Authors

Cited Authors

  • Wiehe, K; Pierce, B; Mintseris, J; Tong, WW; Anderson, R; Chen, R; Weng, Z

Published Date

  • August 1, 2005

Published In

Volume / Issue

  • 60 / 2

Start / End Page

  • 207 - 213

PubMed ID

  • 15981263

Electronic International Standard Serial Number (EISSN)

  • 1097-0134

Digital Object Identifier (DOI)

  • 10.1002/prot.20559


  • eng

Conference Location

  • United States