Brief report: assessing adherence to pediatric antiretroviral regimens using the 24-hour recall interview.


Journal Article

OBJECTIVE: Examine the 24-hr Recall Interview (24RI) for assessing children's antiretroviral medication adherence. METHODS: Caregivers of 54 children with HIV (aged 2-12 years) completed a clinical adherence interview and the 24RI by telephone. Children's viral load and 3-month pharmacy records were obtained. RESULTS: Thirty-seven percent of children missed > or = 1 dose of medicine over 3 days. In 22% of the samples, adherence varied across medications. The 24RI adherence scores (Frequency, Interval, and Dietary Adherence) were moderately reliable across the three interviews. Pharmacy refill rates were significantly related to viral load, and 24RI barriers were marginally significantly related to viral load. CONCLUSIONS: The 24RI, with its systematic, cued recall, and decreased focus on adherence, may reduce socially desirable responding compared to other self-report methods, and reporting adherence barriers may indicate adherence difficulty. However, the validity of the 24RI must be improved to make it a useful measure to include in an adherence assessment battery.

Full Text

Duke Authors

Cited Authors

  • Marhefka, SL; Tepper, VJ; Farley, JJ; Sleasman, JW; Mellins, CA

Published Date

  • October 2006

Published In

Volume / Issue

  • 31 / 9

Start / End Page

  • 989 - 994

PubMed ID

  • 16514050

Pubmed Central ID

  • 16514050

International Standard Serial Number (ISSN)

  • 0146-8693

Digital Object Identifier (DOI)

  • 10.1093/jpepsy/jsj107


  • eng

Conference Location

  • United States