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Past and present treatment of pancreatic adenocarcinoma: Chemotherapy as a standard treatment modality

Publication ,  Journal Article
Abbruzzese, JL
Published in: Seminars in Oncology
2002

Pancreatic cancer continues to be a challenging therapeutic problem, with approximately 28,000 deaths annually in the United States. Most studies of single-agent or combination chemotherapy in the treatment of patients with advanced adenocarcinoma of the pancreas have documented low response rates and little reproducible impact on patient survival or quality of life. However, the recent success of gemcitabine in patients with locally advanced and metastatic pancreatic cancer suggests that systemic therapy can have a beneficial effect on the natural history of this disease. Also, the rapidly evolving understanding of the molecular biology of pancreatic cancer may contribute to the development and use of targeted therapies with novel agents for even more effective treatments in the near future. Copyright 2002, Elsevier Science (USA). All rights reserved.

Duke Scholars

Published In

Seminars in Oncology

ISSN

0093-7754

Publication Date

2002

Volume

29

Issue

6 SUPPL. 20

Start / End Page

2 / 8

Related Subject Headings

  • Oncology & Carcinogenesis
  • 1112 Oncology and Carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Abbruzzese, J. L. (2002). Past and present treatment of pancreatic adenocarcinoma: Chemotherapy as a standard treatment modality. Seminars in Oncology, 29(6 SUPPL. 20), 2–8.
Abbruzzese, J. L. “Past and present treatment of pancreatic adenocarcinoma: Chemotherapy as a standard treatment modality.” Seminars in Oncology 29, no. 6 SUPPL. 20 (2002): 2–8.
Abbruzzese, J. L. “Past and present treatment of pancreatic adenocarcinoma: Chemotherapy as a standard treatment modality.” Seminars in Oncology, vol. 29, no. 6 SUPPL. 20, 2002, pp. 2–8.
Journal cover image

Published In

Seminars in Oncology

ISSN

0093-7754

Publication Date

2002

Volume

29

Issue

6 SUPPL. 20

Start / End Page

2 / 8

Related Subject Headings

  • Oncology & Carcinogenesis
  • 1112 Oncology and Carcinogenesis