Epstein-Barr virus-associated epithelial and mesenchymal neoplasms.

Journal Article (Review)

Epstein-Barr virus (EBV) is a ubiquitous human pathogen that usually maintains a harmonious relationship with its host. Rarely, this host-virus balance is perturbed, causing a diverse group of malignancies in both immunocompetent and immunosuppressed patients. In addition to its role in hematologic malignancies (Burkitt lymphoma, subsets of Hodgkin and T-cell lymphomas, posttransplant lymphomas), EBV has been implicated in both epithelial (undifferentiated nasopharyngeal carcinoma, a subset of gastric adenocarcinomas) and mesenchymal (EBV-associated smooth muscle tumor, inflammatory pseudotumor-like follicular dendritic cell tumor) neoplasms. This review will focus on EBV-associated epithelial and mesenchymal neoplasms.

Full Text

Duke Authors

Cited Authors

  • Deyrup, AT

Published Date

  • April 2008

Published In

Volume / Issue

  • 39 / 4

Start / End Page

  • 473 - 483

PubMed ID

  • 18342658

Electronic International Standard Serial Number (EISSN)

  • 1532-8392

International Standard Serial Number (ISSN)

  • 0046-8177

Digital Object Identifier (DOI)

  • 10.1016/j.humpath.2007.10.030

Language

  • eng