Acyclic cucurbit[n]uril-type molecular containers bind neuromuscular blocking agents in vitro and reverse neuromuscular block in vivo.
Published
Journal Article
Be my guest: two acyclic cucurbit[n]uril-type receptors that carry SO(3) (-) -groups bind tightly to several commonly used neuromuscular blocking agents, such as rocuronium, in aqueous solution as revealed by direct and competitive UV/Vis binding assays. One of these containers functions as a potent reversal agent for rocuronium-induced neuromuscular block in rats.
Full Text
Duke Authors
Cited Authors
- Ma, D; Zhang, B; Hoffmann, U; Sundrup, MG; Eikermann, M; Isaacs, L
Published Date
- November 5, 2012
Published In
Volume / Issue
- 51 / 45
Start / End Page
- 11358 - 11362
PubMed ID
- 23047893
Pubmed Central ID
- 23047893
Electronic International Standard Serial Number (EISSN)
- 1521-3773
Digital Object Identifier (DOI)
- 10.1002/anie.201206031
Language
- eng
Conference Location
- Germany