Renal function outcomes for multifocal renal neoplasms managed by radiofrequency ablation.
PURPOSE: To evaluate renal function changes related to radiofrequency ablation (RFA) for the treatment of multifocal renal neoplasms. METHODS: This is an institutional review board-approved, Health Insurance Portability and Accountability Act compliant retrospective study of all patients treated with computed tomography guided RFA for multifocal renal neoplasms at one institution. Fifty-seven subjects, mean age 70 (range 37-88) years, underwent RFA of 169 renal neoplasms (average size 2.0 cm). Subjects had between 2 and 8 (mean 2.96) neoplasms ablated. Estimated glomerular filtration rate (eGFR) was measured before and after RFA. Complications related to RFA were recorded. RESULTS: eGFR decreased on average of 4.4 % per tumor treated and 6.7 % per ablation session (average 1.76 tumors treated per session). For subjects with the largest neoplasm measuring >3 cm, eGFR decreased an average of 14.5 % during the course of their treatment. If the largest neoplasm measured 2-3 cm, eGFR decreased an average of 7.7 %, and if the largest neoplasm measured <2 cm, eGFR decreased an average of 3.8 %. Subjects with reduced baseline renal function were more likely to have a greater decline in eGFR after RFA. There was a minor complication rate of 6.3 % (6 of 96 sessions), none of which required treatment, and a major complication rate of 4.2 % (4 of 96 sessions). CONCLUSION: RFA for the treatment of multifocal renal neoplasms results in mild decline of renal function.
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Related Subject Headings
- Treatment Outcome
- Tomography, X-Ray Computed
- Retrospective Studies
- Radiography, Interventional
- Nuclear Medicine & Medical Imaging
- Middle Aged
- Male
- Kidney Neoplasms
- Kidney Function Tests
- Kidney
Citation
Published In
DOI
EISSN
Publication Date
Volume
Issue
Start / End Page
Location
Related Subject Headings
- Treatment Outcome
- Tomography, X-Ray Computed
- Retrospective Studies
- Radiography, Interventional
- Nuclear Medicine & Medical Imaging
- Middle Aged
- Male
- Kidney Neoplasms
- Kidney Function Tests
- Kidney