State of the Art: Newer biomarkers in heart failure.


Journal Article (Review)

Since natriuretic peptides were successfully integrated into the clinical practice of heart failure (HF), the possibility of using new biomarkers to advance the management of affected patients has been explored. While a huge number of candidate HF biomarkers have been described recently, very few have made the difficult translation from initial promise to clinical application. These markers mirror the complex pathophysiology of heart failure at various levels: cell loss (troponin), fibrosis (ST2 and galectin-3), infection (procalcitonin), and renal disease (several renal markers). In this review, we examine the best emerging candidates for clinical assessment and management of patients with HF.

Full Text

Duke Authors

Cited Authors

  • de Boer, RA; Daniels, LB; Maisel, AS; Januzzi, JL

Published Date

  • June 2015

Published In

Volume / Issue

  • 17 / 6

Start / End Page

  • 559 - 569

PubMed ID

  • 25880523

Pubmed Central ID

  • 25880523

Electronic International Standard Serial Number (EISSN)

  • 1879-0844

Digital Object Identifier (DOI)

  • 10.1002/ejhf.273


  • eng

Conference Location

  • England