Natriuretic peptides in heart failure with preserved ejection fraction.


Journal Article

Timely diagnosis, early introduction of appropriate treatment, accurate risk stratification, and optimal titration of therapy are all key to the management of acute and chronic heart failure (HF). Plasma concentrations of the cardiac natriuretic peptides (NPs) are valuable aids in each of these elements of care. However, most data are derived from cohorts with undifferentiated HF or HF with reduced ejection fraction (HFREF), and the performance and best application of NPs in HF with preserved ejection fraction (HFPEF) is less certain. This review outlines the evidence for use of NPs in the evaluation and management of HFPEF.

Full Text

Duke Authors

Cited Authors

  • Richards, AM; Januzzi, JL; Troughton, RW

Published Date

  • July 2014

Published In

Volume / Issue

  • 10 / 3

Start / End Page

  • 453 - 470

PubMed ID

  • 24975909

Pubmed Central ID

  • 24975909

International Standard Serial Number (ISSN)

  • 1551-7136

Digital Object Identifier (DOI)

  • 10.1016/j.hfc.2014.04.006


  • eng

Conference Location

  • United States