Natriuretic peptides in heart failure and acute coronary syndrome.


Journal Article (Review)

B-type natriuretic peptide (BNP) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) are the gold standard biomarkers in determining heart failure (HF) diagnosis and prognosis. These natriuretic peptides may also be useful in guiding HF management, but further studies are needed before they can be routinely recommended for that purpose. A novel natriuretic peptide biomarker, mid-regional pro atrial natriuretic peptide (MR-proANP), shows promise in determining diagnosis and prognosis in HF patients. BNP and NT-proBNP may be of use in excluding myocardial infarction and to assist in determining prognosis in acute coronary syndrome (ACS). Therapeutic implication of natriuretic peptides in ACS is unclear.

Full Text

Duke Authors

Cited Authors

  • Gaggin, HK; Januzzi, JL

Published Date

  • March 2014

Published In

Volume / Issue

  • 34 / 1

Start / End Page

  • 43 - vi

PubMed ID

  • 24507786

Pubmed Central ID

  • 24507786

Electronic International Standard Serial Number (EISSN)

  • 1557-9832

Digital Object Identifier (DOI)

  • 10.1016/j.cll.2013.11.007


  • eng

Conference Location

  • United States