Soluble ST2 and galectin-3 in heart failure.


Journal Article (Review)

Circulating biomarkers that directly reflect disease progression, hemodynamics, and ventricular remodeling at a molecular level are critical to risk stratification in heart failure (HF), affording unique insights into pathophysiology not fully captured by traditional risk markers. Despite the wealth of data confirming the importance of natriuretic peptides in HF diagnosis and prognosis, residual clinical risk in HF suggests that additional biomarkers complementary to natriuretic peptides may be useful. In this article, the current literature addressing the role of these biomarkers in the clinical diagnosis and risk stratification in HF is summarized.

Full Text

Duke Authors

Cited Authors

  • Shah, RV; Januzzi, JL

Published Date

  • March 2014

Published In

Volume / Issue

  • 34 / 1

Start / End Page

  • 87 - vii

PubMed ID

  • 24507789

Pubmed Central ID

  • 24507789

Electronic International Standard Serial Number (EISSN)

  • 1557-9832

Digital Object Identifier (DOI)

  • 10.1016/j.cll.2013.11.009


  • eng

Conference Location

  • United States