Natriuretic peptide-guided management of acutely destabilized heart failure: rationale and treatment algorithm.


Journal Article (Review)

Natriuretic peptides (B-type natriuretic peptide [BNP] and N-terminal pro-B-type natriuretic peptide [NT]-proBNP) have been proven to be strong diagnostic and prognostic tools in the assessment of acutely decompensated heart failure. The emergence of BNP/NT-proBNP testing as a standard of care in this setting has helped to reduce healthcare costs, and may decrease adverse clinical outcomes. The use of BNP and NT-proBNP to "guide" treatment of acutely destabilized heart failure has recently grown. We present an overview of the value of BNP/NT-proBNP in the context of acute heart failure management and therapy optimization, and present an algorithm for natriuretic peptide-guided treatment of acutely destabilized heart failure.

Full Text

Duke Authors

Cited Authors

  • Bhardwaj, A; Januzzi, JL

Published Date

  • December 2009

Published In

Volume / Issue

  • 8 / 4

Start / End Page

  • 146 - 150

PubMed ID

  • 19952548

Pubmed Central ID

  • 19952548

Electronic International Standard Serial Number (EISSN)

  • 1535-2811

Digital Object Identifier (DOI)

  • 10.1097/HPC.0b013e3181c4a0c6


  • eng

Conference Location

  • United States