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A new synthetic approach to 2,3-dideoxy-2-fluoro-β-D-threo- pentofuranose, the fluorofuranose unit of the anti-HIV-active nucleoside, β-FddA

Publication ,  Journal Article
Caille, JC; Miel, H; Armstrong, P; McKervey, MA
Published in: Tetrahedron Letters
January 19, 2004

The fluorinated furanose unit of the anti-HIV-active nucleoside (2,3-dideoxy-2-fluoro-β-D-threo-pentofuranosyl)adenine, β-FddA, has been synthesized as its 5-trityl derivative with high stereocontrol from (S)-trityl glycidol and phenylthioacetic acid. © 2003 Elsevier Ltd. All rights reserved.

Duke Scholars

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

January 19, 2004

Volume

45

Issue

4

Start / End Page

863 / 865

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry
 

Citation

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Caille, J. C., Miel, H., Armstrong, P., & McKervey, M. A. (2004). A new synthetic approach to 2,3-dideoxy-2-fluoro-β-D-threo- pentofuranose, the fluorofuranose unit of the anti-HIV-active nucleoside, β-FddA. Tetrahedron Letters, 45(4), 863–865. https://doi.org/10.1016/j.tetlet.2003.11.020
Caille, J. C., H. Miel, P. Armstrong, and M. A. McKervey. “A new synthetic approach to 2,3-dideoxy-2-fluoro-β-D-threo- pentofuranose, the fluorofuranose unit of the anti-HIV-active nucleoside, β-FddA.” Tetrahedron Letters 45, no. 4 (January 19, 2004): 863–65. https://doi.org/10.1016/j.tetlet.2003.11.020.
Caille, J. C., et al. “A new synthetic approach to 2,3-dideoxy-2-fluoro-β-D-threo- pentofuranose, the fluorofuranose unit of the anti-HIV-active nucleoside, β-FddA.” Tetrahedron Letters, vol. 45, no. 4, Jan. 2004, pp. 863–65. Scopus, doi:10.1016/j.tetlet.2003.11.020.
Caille JC, Miel H, Armstrong P, McKervey MA. A new synthetic approach to 2,3-dideoxy-2-fluoro-β-D-threo- pentofuranose, the fluorofuranose unit of the anti-HIV-active nucleoside, β-FddA. Tetrahedron Letters. 2004 Jan 19;45(4):863–865.
Journal cover image

Published In

Tetrahedron Letters

DOI

ISSN

0040-4039

Publication Date

January 19, 2004

Volume

45

Issue

4

Start / End Page

863 / 865

Related Subject Headings

  • Organic Chemistry
  • 3405 Organic chemistry
  • 3404 Medicinal and biomolecular chemistry
  • 3101 Biochemistry and cell biology
  • 0305 Organic Chemistry
  • 0304 Medicinal and Biomolecular Chemistry