Anticoagulant therapy in unstable angina.

Journal Article (Journal Article;Review)

The goal of anticoagulant therapy in unstable angina is to prevent progression of a subocclusive coronary thrombus to complete occlusion of the coronary artery, thereby preventing myocardial infarction and death. Although these have been many advances in therapy with anticoagulants, considerable morbidity and mortality remains. Also, although combination therapy with potent novel anticoagulants and antiplatelet agents may be an alternative strategy, this needs to be balanced against the risks of hemorrhagic complications. More precise and biologically relevant methods of monitoring anticoagulant effect, along with appropriately modified doses given in combination offers promise.

Full Text

Duke Authors

Cited Authors

  • Choy, JB; Armstrong, PW

Published Date

  • May 1999

Published In

Volume / Issue

  • 17 / 2

Start / End Page

  • 327 - ix

PubMed ID

  • 10384830

International Standard Serial Number (ISSN)

  • 0733-8651

Digital Object Identifier (DOI)

  • 10.1016/s0733-8651(05)70078-3


  • eng

Conference Location

  • Netherlands