Synthesis of the putative structures of homopumiliotoxins 235C and 233F

Journal Article (Journal Article)

A novel approach to diene based quinolizidines, using an intramolecular Heck reaction in which the vinyl bromide double bond undergoes inversion of configuration, is reported. These quinolizidines have previously been proposed as tentative structures for homopumiliotoxin alkaloids 233F and 235C. The mass spectral data of the synthetic materials were different to those of the natural products confirming that the original structures need to be revised. © 2004 Elsevier Ltd. All rights reserved.

Full Text

Duke Authors

Cited Authors

  • Armstrong, P; Feutren, S; McAlonan, H; O'Mahony, G; Stevenson, PJ

Published Date

  • February 16, 2004

Published In

Volume / Issue

  • 45 / 8

Start / End Page

  • 1627 - 1630

International Standard Serial Number (ISSN)

  • 0040-4039

Digital Object Identifier (DOI)

  • 10.1016/j.tetlet.2003.12.126

Citation Source

  • Scopus