Do You Want to Hear the Bad News? The Value of Diagnostic Tests for Alzheimer's Disease.

Journal Article (Journal Article)

OBJECTIVE: The diagnosis of Alzheimer's disease (AD) remains difficult. Lack of diagnostic certainty or possible distress related to a positive result from diagnostic testing could limit the application of new testing technologies. The objective of this paper is to quantify respondents' preferences for obtaining AD diagnostic tests and to estimate the perceived value of AD test information. METHODS: Discrete-choice experiment and contingent-valuation questions were administered to respondents in Germany and the United Kingdom. Choice data were analyzed by using random-parameters logit. A probit model characterized respondents who were not willing to take a test. RESULTS: Most respondents indicated a positive value for AD diagnostic test information. Respondents who indicated an interest in testing preferred brain imaging without the use of radioactive markers. German respondents had relatively lower money-equivalent values for test features compared with respondents in the United Kingdom. CONCLUSIONS: Respondents preferred less invasive diagnostic procedures and tests with higher accuracy and expressed a willingness to pay up to €700 to receive a less invasive test with the highest accuracy.

Full Text

Duke Authors

Cited Authors

  • Mühlbacher, A; Johnson, FR; Yang, J-C; Happich, M; Belger, M

Published Date

  • January 2016

Published In

Volume / Issue

  • 19 / 1

Start / End Page

  • 66 - 74

PubMed ID

  • 26797238

Electronic International Standard Serial Number (EISSN)

  • 1524-4733

Digital Object Identifier (DOI)

  • 10.1016/j.jval.2015.10.011


  • eng

Conference Location

  • United States