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Keratomalacia in a Patient With Psychogenic Vitamin A Deficiency.

Publication ,  Journal Article
Gospe, SM; Todorich, B; Foster, YG; Legault, G; Woods, SK; Proia, AD; Daluvoy, M
Published in: Cornea
March 2016

PURPOSE: To report the clinical and histopathological findings of a patient with bilateral keratomalacia arising from severe vitamin A deficiency from panic disorder-related malnutrition. METHODS: Case report. RESULTS: A 47-year-old male with panic disorder presented with 1 month of painful vision loss sequentially affecting the right and left eyes. He exhibited bilateral conjunctival xerosis with complete corneal melt in the right eye and a large corneal epithelial defect with underlying anterior chamber inflammation in the left eye. Laboratory investigation revealed undetectable serum vitamin A levels attributed to self-induced vomiting and starvation. He was treated with high-dose vitamin A, but the right eye required enucleation. The histological findings are reported. CONCLUSIONS: Vitamin A deficiency in the absence of organic gastrointestinal abnormalities is exceedingly rare in the developed world. A strong index of suspicion and thorough review of systems are invaluable in evaluating patients with unexplained corneal melt.

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Published In

Cornea

DOI

EISSN

1536-4798

Publication Date

March 2016

Volume

35

Issue

3

Start / End Page

405 / 407

Location

United States

Related Subject Headings

  • Xerophthalmia
  • Vitamin A Deficiency
  • Panic Disorder
  • Ophthalmology & Optometry
  • Middle Aged
  • Malnutrition
  • Male
  • Humans
  • Corneal Ulcer
  • 3212 Ophthalmology and optometry
 

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Gospe, S. M., Todorich, B., Foster, Y. G., Legault, G., Woods, S. K., Proia, A. D., & Daluvoy, M. (2016). Keratomalacia in a Patient With Psychogenic Vitamin A Deficiency. Cornea, 35(3), 405–407. https://doi.org/10.1097/ICO.0000000000000732
Gospe, Sidney M., Bozho Todorich, Yevgeniya G. Foster, Gary Legault, Suzanne K. Woods, Alan D. Proia, and Melissa Daluvoy. “Keratomalacia in a Patient With Psychogenic Vitamin A Deficiency.Cornea 35, no. 3 (March 2016): 405–7. https://doi.org/10.1097/ICO.0000000000000732.
Gospe SM, Todorich B, Foster YG, Legault G, Woods SK, Proia AD, et al. Keratomalacia in a Patient With Psychogenic Vitamin A Deficiency. Cornea. 2016 Mar;35(3):405–7.
Gospe, Sidney M., et al. “Keratomalacia in a Patient With Psychogenic Vitamin A Deficiency.Cornea, vol. 35, no. 3, Mar. 2016, pp. 405–07. Pubmed, doi:10.1097/ICO.0000000000000732.
Gospe SM, Todorich B, Foster YG, Legault G, Woods SK, Proia AD, Daluvoy M. Keratomalacia in a Patient With Psychogenic Vitamin A Deficiency. Cornea. 2016 Mar;35(3):405–407.

Published In

Cornea

DOI

EISSN

1536-4798

Publication Date

March 2016

Volume

35

Issue

3

Start / End Page

405 / 407

Location

United States

Related Subject Headings

  • Xerophthalmia
  • Vitamin A Deficiency
  • Panic Disorder
  • Ophthalmology & Optometry
  • Middle Aged
  • Malnutrition
  • Male
  • Humans
  • Corneal Ulcer
  • 3212 Ophthalmology and optometry