Clinical and neuroimaging features as diagnostic guides in neonatal neurology diseases with cerebellar involvement.

Published online

Journal Article (Review)

Cerebellar abnormalities are encountered in a high number of neurological diseases that present in the neonatal period. These disorders can be categorized broadly as inherited (e.g. malformations, inborn errors of metabolism) or acquired (e.g. hemorrhages, infections, stroke). In some disorders such as Dandy-Walker malformation or Joubert syndrome, the main abnormalities are located within the cerebellum and brainstem. In other disorders such as Krabbe disease or sulfite oxidase deficiency, the main abnormalities are found within the supratentorial brain, but the cerebellar involvement may be helpful for diagnostic purposes. In In this article, we review neurological disorders with onset in the neonatal period and cerebellar involvement with a focus on how characterization of cerebellar involvement can facilitate accurate diagnosis and improved accuracy of neuro-functional prognosis.

Full Text

Duke Authors

Cited Authors

  • Klein, JL; Lemmon, ME; Northington, FJ; Boltshauser, E; Huisman, TAGM; Poretti, A

Published Date

  • 2016

Published In

Volume / Issue

  • 3 /

Start / End Page

  • 1 -

PubMed ID

  • 26770813

Pubmed Central ID

  • 26770813

International Standard Serial Number (ISSN)

  • 2053-8871

Digital Object Identifier (DOI)

  • 10.1186/s40673-016-0039-1

Language

  • eng

Conference Location

  • England