Algorithm for the management of ERCP-related perforations.

Journal Article (Journal Article)

BACKGROUND AND AIMS: Perforation is a rare but serious adverse event of ERCP. There is no consensus to guide the clinician on the management of ERCP-related perforations, with particular controversy surrounding the immediate surgical management of postprocedurally detected duodenal perforation because of overextension of a sphincterotomy. Our aim was to assess patient outcomes using a predetermined algorithm based on managing ERCP-related duodenal perforations according to the mechanism of injury. METHODS: A retrospective single-center study of all consecutive patients with Stapfer type I and II perforations between 2000 and 2014 were included. Our institutional algorithm since 2000 dictated that Stapfer type I perforations (duodenal wall perforation, endoscope related) should be managed surgically unless prohibited by underlying comorbidities and Stapfer type II perforations (periampullary, sphincterotomy related) managed nonsurgically unless a deterioration in clinical status necessitated surgery. RESULTS: Sixty-one patients (mean age, 51 years; 80% women) were analyzed with Stapfer type I perforations diagnosed in 7 (11%) and type II in 54 (89%). A postprocedural diagnosis of perforation was made in 55 patients (90%). Four patients (7%) had Stapfer type II perforations that failed medical management and required surgery. The mean length of stay (LOS) in the entire cohort was 9.6 days with a low mortality rate of 3%. Systemic inflammatory response syndrome was observed in 18 patients (33%) with Stapfer type II perforations and was not associated with the need for surgery. Concurrent post-ERCP pancreatitis was diagnosed in 26 patients (43%) and was associated with an increased LOS. CONCLUSIONS: Stapfer type II perforations have excellent outcomes when managed medically. We validate an algorithm for the management of ERCP-related perforations and propose that it should function as a guide.

Full Text

Duke Authors

Cited Authors

  • Kumbhari, V; Sinha, A; Reddy, A; Afghani, E; Cotsalas, D; Patel, YA; Storm, AC; Khashab, MA; Kalloo, AN; Singh, VK

Published Date

  • May 2016

Published In

Volume / Issue

  • 83 / 5

Start / End Page

  • 934 - 943

PubMed ID

  • 26439541

Electronic International Standard Serial Number (EISSN)

  • 1097-6779

Digital Object Identifier (DOI)

  • 10.1016/j.gie.2015.09.039


  • eng

Conference Location

  • United States