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Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes.

Publication ,  Journal Article
Omotosho, P; Mor, A; Shantavasinkul, PC; Corsino, L; Torquati, A
Published in: Surg Endosc
July 2016

OBJECTIVE: To evaluate the impact of Roux-en-Y gastric bypass (RYGB) on quality of life in obese diabetic patients compared to standard medical therapy for type 2 diabetes mellitus. METHODS: We prospectively studied two matched obese populations with type 2 diabetes. Thirty patients underwent laparoscopic RYGB and 31 received standard medical therapy combined with a diabetes support and education program (DSE), consisting of educational sessions on diet and exercise. Groups were matched by age, gender, weight, glucostatic parameters, and use of glucose-lowering medications (oral agents and insulin therapy). Health-related quality of life (HRQOL) was assessed using the normalized SF-36 questionnaire, and data were collected at baseline and at 12-month follow-up. RESULTS: Diabetic patients who underwent RYGB experienced a statistically significant increase in their overall HRQOL. However, the role-physical and mental health domains increased but did not reach statistical significance. Diabetic patients in the medical therapy and DSE group did not show any significant increase in HRQOL. The between-group differences for the HRQOL changes from baseline were significant, other than for role-physical and mental health domains. Percentage changes in glucostatic parameters, discontinuation of glucose-lowering medications, and T2DM remission were not found to predict the percentage change in SF-36 scores at 12 months after RYGB. CONCLUSIONS: For the first time, with a prospective matched control study, we demonstrate a significant improvement in HRQOL in obese diabetic patients who underwent RYGB, but not in those who were offered standard medical therapy and DSE.

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Published In

Surg Endosc

DOI

EISSN

1432-2218

Publication Date

July 2016

Volume

30

Issue

7

Start / End Page

2857 / 2864

Location

Germany

Related Subject Headings

  • Weight Loss
  • Surgery
  • Quality of Life
  • Prospective Studies
  • Obesity, Morbid
  • Middle Aged
  • Mental Health
  • Male
  • Laparoscopy
  • Insulin
 

Citation

APA
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ICMJE
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Omotosho, P., Mor, A., Shantavasinkul, P. C., Corsino, L., & Torquati, A. (2016). Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes. Surg Endosc, 30(7), 2857–2864. https://doi.org/10.1007/s00464-015-4568-0
Omotosho, Philip, Alessandro Mor, Prapimporn Chattranukulchai Shantavasinkul, Leonor Corsino, and Alfonso Torquati. “Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes.Surg Endosc 30, no. 7 (July 2016): 2857–64. https://doi.org/10.1007/s00464-015-4568-0.
Omotosho P, Mor A, Shantavasinkul PC, Corsino L, Torquati A. Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes. Surg Endosc. 2016 Jul;30(7):2857–64.
Omotosho, Philip, et al. “Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes.Surg Endosc, vol. 30, no. 7, July 2016, pp. 2857–64. Pubmed, doi:10.1007/s00464-015-4568-0.
Omotosho P, Mor A, Shantavasinkul PC, Corsino L, Torquati A. Gastric bypass significantly improves quality of life in morbidly obese patients with type 2 diabetes. Surg Endosc. 2016 Jul;30(7):2857–2864.
Journal cover image

Published In

Surg Endosc

DOI

EISSN

1432-2218

Publication Date

July 2016

Volume

30

Issue

7

Start / End Page

2857 / 2864

Location

Germany

Related Subject Headings

  • Weight Loss
  • Surgery
  • Quality of Life
  • Prospective Studies
  • Obesity, Morbid
  • Middle Aged
  • Mental Health
  • Male
  • Laparoscopy
  • Insulin