Genetic/Familial High-Risk Assessment: Breast and Ovarian, Version 2.2015.


Journal Article

The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast and Ovarian provide recommendations for genetic testing and counseling and risk assessment and management for hereditary cancer syndromes. Guidelines focus on syndromes associated with an increased risk of breast and/or ovarian cancer and are intended to assist with clinical and shared decision-making. These NCCN Guidelines Insights summarize major discussion points of the 2015 NCCN Genetic/Familial High-Risk Assessment: Breast and Ovarian panel meeting. Major discussion topics this year included multigene testing, risk management recommendations for less common genetic mutations, and salpingectomy for ovarian cancer risk reduction. The panel also discussed revisions to genetic testing criteria that take into account ovarian cancer histology and personal history of pancreatic cancer.

Full Text

Duke Authors

Cited Authors

  • Daly, MB; Pilarski, R; Axilbund, JE; Berry, M; Buys, SS; Crawford, B; Farmer, M; Friedman, S; Garber, JE; Khan, S; Klein, C; Kohlmann, W; Kurian, A; Litton, JK; Madlensky, L; Marcom, PK; Merajver, SD; Offit, K; Pal, T; Rana, H; Reiser, G; Robson, ME; Shannon, KM; Swisher, E; Voian, NC; Weitzel, JN; Whelan, A; Wick, MJ; Wiesner, GL; Dwyer, M; Kumar, R; Darlow, S

Published Date

  • February 2016

Published In

Volume / Issue

  • 14 / 2

Start / End Page

  • 153 - 162

PubMed ID

  • 26850485

Pubmed Central ID

  • 26850485

Electronic International Standard Serial Number (EISSN)

  • 1540-1413


  • eng

Conference Location

  • United States