Neoadjuvant use of ipilimumab in locally advanced melanoma.

Journal Article (Journal Article)

Recent advances in immune modulating therapies show great promise for patients with advanced melanoma, however optimal strategies for achieving long-term disease control in locally advanced melanoma are unclear. We present two cases of neoadjuvant ipilimumab, one case in combination with isolated limb infusion (ILI) followed by surgical resection and one followed by surgery alone. Both patients have had durable responses. These cases highlight the ongoing need for prospective trials in the neoadjuvant setting.

Full Text

Duke Authors

Cited Authors

  • Howie, LJ; Tyler, DS; Salama, AKS

Published Date

  • December 2015

Published In

Volume / Issue

  • 112 / 8

Start / End Page

  • 841 - 843

PubMed ID

  • 26768512

Electronic International Standard Serial Number (EISSN)

  • 1096-9098

Digital Object Identifier (DOI)

  • 10.1002/jso.24079


  • eng

Conference Location

  • United States