Emerging Concepts in Paracrine Mechanisms in Regenerative Cardiovascular Medicine and Biology.

Journal Article (Journal Article;Review)

In the past decade, substantial evidence supports the paradigm that stem cells exert their reparative and regenerative effects, in large part, through the release of biologically active molecules acting in a paracrine fashion on resident cells. The data suggest the existence of a tissue microenvironment where stem cell factors influence cell survival, inflammation, angiogenesis, repair, and regeneration in a temporal and spatial manner.

Full Text

Duke Authors

Cited Authors

  • Hodgkinson, CP; Bareja, A; Gomez, JA; Dzau, VJ

Published Date

  • January 8, 2016

Published In

Volume / Issue

  • 118 / 1

Start / End Page

  • 95 - 107

PubMed ID

  • 26837742

Pubmed Central ID

  • PMC4874329

Electronic International Standard Serial Number (EISSN)

  • 1524-4571

Digital Object Identifier (DOI)

  • 10.1161/CIRCRESAHA.115.305373


  • eng

Conference Location

  • United States