Self-assembling polymer-peptide conjugates: Nanostructural tailoring


Journal Article

Modulation of nanoscale assembly of febrils by incorporating polyethylene glycol into the backbone of self assembling β-sheets was analyzed. Insertion of nonpeptide random-coil-forming polymers within the peptide backbone modulated βsheet fibril dimensions. It was found that Q11-PEG produced different nanostructures from unmodified Q11. Alternative Methods for producing β-sheet peptide PEG copolymers broadened the synthetic possibilities for producing the structures.

Full Text

Cited Authors

  • Collier, JH; Messersmith, PB

Published Date

  • June 4, 2004

Published In

Volume / Issue

  • 16 / 11

Start / End Page

  • 907 - 910

International Standard Serial Number (ISSN)

  • 0935-9648

Digital Object Identifier (DOI)

  • 10.1002/adma.200306379

Citation Source

  • Scopus