Generation of bone marrow and fetal liver chimeric mice.

Published

Journal Article

The creation of bone marrow and fetal liver chimeric mice has proven to be a valuable tool in the field of immunology. Chimeric mice are used to study the contribution of various cell types of hematopoietic versus non-hematopoietic origin in the course of an immune response. In this chapter, we describe a detailed method to obtain bone marrow or fetal liver chimeric mice and assess the efficiency of donor cells to repopulate the hematopoietic compartment of recipient mice.

Full Text

Published version (via Digital Object Identifier)
Pubmed Central version

Duke Authors

Holl, Eda K

Cited Authors

Holl, EK

Published Date

January 2013

Published In

Methods in Molecular Biology (Clifton, N.J.)

Volume / Issue

1032 /

Start / End Page

315 - 321

PubMed ID

23943463

Pubmed Central ID

23943463

Electronic International Standard Serial Number (EISSN)

1940-6029

International Standard Serial Number (ISSN)

1064-3745

Digital Object Identifier (DOI)

10.1007/978-1-62703-496-8_24

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