Generation of bone marrow and fetal liver chimeric mice.

Journal Article (Journal Article)

The creation of bone marrow and fetal liver chimeric mice has proven to be a valuable tool in the field of immunology. Chimeric mice are used to study the contribution of various cell types of hematopoietic versus non-hematopoietic origin in the course of an immune response. In this chapter, we describe a detailed method to obtain bone marrow or fetal liver chimeric mice and assess the efficiency of donor cells to repopulate the hematopoietic compartment of recipient mice.

Full Text

Duke Authors

Cited Authors

  • Holl, EK

Published Date

  • 2013

Published In

Volume / Issue

  • 1032 /

Start / End Page

  • 315 - 321

PubMed ID

  • 23943463

Pubmed Central ID

  • PMC3947880

Electronic International Standard Serial Number (EISSN)

  • 1940-6029

Digital Object Identifier (DOI)

  • 10.1007/978-1-62703-496-8_24


  • eng

Conference Location

  • United States