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Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients with Severe Functional Tricuspid Regurgitation.

Publication ,  Journal Article
Park, J-B; Kim, H-K; Jung, J-H; Klem, I; Yoon, YE; Lee, S-P; Park, E-A; Hwang, H-Y; Lee, W; Kim, K-H; Kim, Y-J; Cho, G-Y; Kim, K-B; Sohn, D-W; Ahn, H
Published in: Radiology
September 2016

Purpose To explore the prognostic value of cardiac magnetic resonance (MR) imaging in predicting postoperative cardiac death in patients with severe functional tricuspid regurgitation (TR). Materials and Methods This study was approved by the institutional review board, and written informed consent was obtained from all patients. Prospectively collected data included cardiac MR images, New York Heart Association (NYHA) functional class, a comprehensive laboratory test, and clinical events over the follow-up period in 75 consecutive patients (61 women and 14 men; mean age ± standard deviation, 59 years ± 9) undergoing corrective surgery for severe functional TR. Cox proportional hazards models were used to assess the association between cardiac MR parameters and outcomes. Results During a median follow-up period of 57 months (range, 21-82 months), cardiac mortality and all-cause mortality were 17.3% and 26.7%, respectively, with a surgical mortality of 6.7%. Cardiac death risk was lower with a higher right ventricular (RV) ejection fraction (EF) on cardiac MR images (hazard ratio per 5% higher EF = 0.790, P = .048). By adjusting for confounding variables, RV EF remained a significant predictor for cardiac death (P < .05) and major postoperative cardiac events (P < .05). The area under the receiver operating characteristic curve (AUC) confirmed the incremental role of RV EF on cardiac MR images in the prediction of postoperative cardiac death (AUC, 0.681-0.771; P = .041) and major postoperative cardiac events (AUC, 0.660-0.745; P = .044) on top of NYHA class. RV end-systolic volume index was also independently associated with these outcomes but failed to increase the AUC significantly. Conclusion Preoperative assessment of cardiac MR imaging-based RV EF provides independent and incremental prognostic information in patients undergoing corrective surgery for severe functional TR. (©) RSNA, 2016 Online supplemental material is available for this article.

Duke Scholars

Published In

Radiology

DOI

EISSN

1527-1315

Publication Date

September 2016

Volume

280

Issue

3

Start / End Page

723 / 734

Location

United States

Related Subject Headings

  • Tricuspid Valve Insufficiency
  • Treatment Outcome
  • Survival Rate
  • Reproducibility of Results
  • Prospective Studies
  • Prognosis
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Park, J.-B., Kim, H.-K., Jung, J.-H., Klem, I., Yoon, Y. E., Lee, S.-P., … Ahn, H. (2016). Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients with Severe Functional Tricuspid Regurgitation. Radiology, 280(3), 723–734. https://doi.org/10.1148/radiol.2016151556
Park, Jun-Bean, Hyung-Kwan Kim, Ji-Hyun Jung, Igor Klem, Yeonyee E. Yoon, Seung-Pyo Lee, Eun-Ah Park, et al. “Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients with Severe Functional Tricuspid Regurgitation.Radiology 280, no. 3 (September 2016): 723–34. https://doi.org/10.1148/radiol.2016151556.
Park J-B, Kim H-K, Jung J-H, Klem I, Yoon YE, Lee S-P, et al. Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients with Severe Functional Tricuspid Regurgitation. Radiology. 2016 Sep;280(3):723–34.
Park, Jun-Bean, et al. “Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients with Severe Functional Tricuspid Regurgitation.Radiology, vol. 280, no. 3, Sept. 2016, pp. 723–34. Pubmed, doi:10.1148/radiol.2016151556.
Park J-B, Kim H-K, Jung J-H, Klem I, Yoon YE, Lee S-P, Park E-A, Hwang H-Y, Lee W, Kim K-H, Kim Y-J, Cho G-Y, Kim K-B, Sohn D-W, Ahn H. Prognostic Value of Cardiac MR Imaging for Preoperative Assessment of Patients with Severe Functional Tricuspid Regurgitation. Radiology. 2016 Sep;280(3):723–734.

Published In

Radiology

DOI

EISSN

1527-1315

Publication Date

September 2016

Volume

280

Issue

3

Start / End Page

723 / 734

Location

United States

Related Subject Headings

  • Tricuspid Valve Insufficiency
  • Treatment Outcome
  • Survival Rate
  • Reproducibility of Results
  • Prospective Studies
  • Prognosis
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Magnetic Resonance Imaging