The Ties that Bind (the Igh Locus).

Journal Article (Journal Article)

Immunoglobulin heavy-chain locus V(D)J recombination requires a 3D chromatin organization which permits widely distributed variable (V) gene segments to contact distant diversity (D) and joining (J) gene segments. A recent study has identified key nodes in the locus interactome, paving the way for new molecular insights into how the locus is configured for recombination.

Full Text

Duke Authors

Cited Authors

  • Krangel, MS

Published Date

  • May 2016

Published In

Volume / Issue

  • 32 / 5

Start / End Page

  • 253 - 255

PubMed ID

  • 27012539

Pubmed Central ID

  • PMC4842146

International Standard Serial Number (ISSN)

  • 0168-9525

Digital Object Identifier (DOI)

  • 10.1016/j.tig.2016.03.003


  • eng

Conference Location

  • England