Heritability of Health and Aging Limitations on Personally Desired Activities.

Published online

Journal Article

The aim of this study is to estimate heritability of incident limitations on personally desired activities within the eighth decade of life. We measured self-rated ability to perform ten personally desired activities in 1606 male veteran twin pairs at baseline and four years later. At follow-up, 33% of the cohort reported more limitations in desired activities. Among twins who completed both assessments, there were no statistically significant differences in incidence rates of limitations as a function of zygosity. Sensitivity tests showed the same for change scores; and that, if cognitive impairment or death are deemed to belong among limitations of desired activities, zygosity contributed 10% to new limitations at follow-up. Maintaining personally desired activities over four years in the eighth decade is not subject to substantial genetic influence. However, if death and cognitive impairment are added to incident limitations, then genetics plays a modest role. In all cases, unique environment is the predominant influence.

Full Text

Duke Authors

Cited Authors

  • Gurland, BJ; Page, W; Small, B; McArdle, JJ; Plassman, BL

Published Date

  • September 30, 2015

Published In

Volume / Issue

  • 3 / 2

Start / End Page

  • 1981 -

PubMed ID

  • 26973959

Pubmed Central ID

  • 26973959

International Standard Serial Number (ISSN)

  • 2420-8124

Digital Object Identifier (DOI)

  • 10.4081/hpr.2015.1981


  • eng

Conference Location

  • Italy