Biomaterials for the central nervous system.
Journal Article (Review;Journal Article)
Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.
Full Text
Duke Authors
Cited Authors
- Zhong, Y; Bellamkonda, RV
Published Date
- September 2008
Published In
Volume / Issue
- 5 / 26
Start / End Page
- 957 - 975
PubMed ID
- 18477539
Pubmed Central ID
- PMC2475552
Electronic International Standard Serial Number (EISSN)
- 1742-5662
International Standard Serial Number (ISSN)
- 1742-5689
Digital Object Identifier (DOI)
- 10.1098/rsif.2008.0071
Language
- eng