Biomaterials for the central nervous system.

Journal Article (Review;Journal Article)

Biomaterials are widely used to help treat neurological disorders and/or improve functional recovery in the central nervous system (CNS). This article reviews the application of biomaterials in (i) shunting systems for hydrocephalus, (ii) cortical neural prosthetics, (iii) drug delivery in the CNS, (iv) hydrogel scaffolds for CNS repair, and (v) neural stem cell encapsulation for neurotrauma. The biological and material requirements for the biomaterials in these applications are discussed. The difficulties that the biomaterials might face in each application and the possible solutions are also reviewed in this article.

Full Text

Duke Authors

Cited Authors

  • Zhong, Y; Bellamkonda, RV

Published Date

  • September 2008

Published In

Volume / Issue

  • 5 / 26

Start / End Page

  • 957 - 975

PubMed ID

  • 18477539

Pubmed Central ID

  • PMC2475552

Electronic International Standard Serial Number (EISSN)

  • 1742-5662

International Standard Serial Number (ISSN)

  • 1742-5689

Digital Object Identifier (DOI)

  • 10.1098/rsif.2008.0071


  • eng