Carcinoma of the lung in the absence of asbestosis: The value of lung fiber burden analysis.

Journal Article (Journal Article)

Asbestos is universally recognized as a carcinogen for the lower respiratory tract. However, asbestos is a contributory factor in a small fraction of lung cancers, the vast majority of which are related to cigarette smoking. The challenge for the pathologist is to determine when a lung cancer may be attributed to past asbestos exposure. The finding of asbestosis either clinically or pathologically is a useful marker for such a determination. However, in the absence of asbestosis, it has been suggested that a fiber burden as determined by analytical electron microscopy within the range of asbestosis is sufficient for determination of a causal contribution. We report here an example of a case of lung cancer in which fiber burden studies showed an asbestos concentration within the range of asbestosis as determined by scanning electron microscopy (SEM).

Full Text

Duke Authors

Cited Authors

  • Roggli, VL; Sporn, TA

Published Date

  • May 2016

Published In

Volume / Issue

  • 40 / 3

Start / End Page

  • 151 - 154

PubMed ID

  • 27043967

Electronic International Standard Serial Number (EISSN)

  • 1521-0758

Digital Object Identifier (DOI)

  • 10.3109/01913123.2016.1154915


  • eng

Conference Location

  • England