[The mechanism of the antitumor effect of total/subtotal radiotherapy with non-tumoricidal doses of radiation].


Journal Article

The myelodepression at therapy for solid malignancies is considered as a mediating element of common antineoplastic activity on the basis of ability of stem cells of hemapoietic system to participate in regeneration of the various tissues of the body, including tumor. The equivalence of the therapeutic benefit mediated by both mild myelodepression due to total/subtotal radiation exposure and conventional chemotherapy with cytotoxic drugs is argued.

Full Text

Duke Authors

Cited Authors

  • Shutko, AN; Akushevich, IV; Ekimova, LP; Mus, VF; Sokurenko, BP; Iurkova, LE; Matiurin, KS

Published Date

  • January 2013

Published In

Volume / Issue

  • 59 / 4

Start / End Page

  • 475 - 478

PubMed ID

  • 24032222

Pubmed Central ID

  • 24032222

International Standard Serial Number (ISSN)

  • 0507-3758


  • rus