Variation of death risk among cancer patients vis-a-vis individualized therapy

Journal Article

To investigate the deviation of survival curves from monotonous shape, 17 curves for 6 most common cancer sites of 87,205 patients (aged 30-89) were selected from The U.S. Surveillance, Epidemiology and End Results (SEER) Register database. The curves were analyzed using monotonous exponential and harmonic functions which allowed a corresponding estimation of quasi-sinusoidal disturbances of monthly death hazard. Detectable fluctuations of the latter were established in the 0-40 - month life span zone depending on tumor site and age at diagnosis.

Duke Authors

Cited Authors

  • Shoutko, AN; Akushevich, I; Ekimova, LP; Karamullin, MA

Published Date

  • November 1, 2010

Published In

Volume / Issue

  • 56 / 4

Start / End Page

  • 430 - 434

International Standard Serial Number (ISSN)

  • 0507-3758

Citation Source

  • Scopus