Choroidal Thickness and En Face Optical Coherence Tomography Imaging in Autoimmune Retinopathy.

Journal Article (Journal Article)

A 57-year-old white woman developed autoimmune retinopathy (AIR) in both eyes associated with bilateral autoimmune sensorineural hearing loss. Laboratory testing was positive for 68kDa (heat-shock protein) and 136kDa (human interstitial retinoid-binding protein). Extensive cancer screening was negative. Spectral-domain optical coherence tomography enhanced depth imaging demonstrated a markedly thickened choroid in both eyes. En face imaging showed a distinctive pattern of granular hyperreflective foveal dots. The concurrent sensorineural hearing loss was thought to be of autoimmune origin and also responded to immunosuppressive treatment. Eyes with non-paraneoplastic, seropositive AIR may have associated increased choroidal thickness. Audiology testing should be considered.

Full Text

Duke Authors

Cited Authors

  • Polascik, BA; Grewal, DS; Jiramongkolchai, K; Fekrat, S

Published Date

  • April 1, 2016

Published In

Volume / Issue

  • 47 / 4

Start / End Page

  • 362 - 365

PubMed ID

  • 27065377

Electronic International Standard Serial Number (EISSN)

  • 2325-8179

Digital Object Identifier (DOI)

  • 10.3928/23258160-20160324-10


  • eng

Conference Location

  • United States