Two new ursane-type triterpenoid saponins from Elsholtzia bodinieri.

Journal Article

Two new ursane-type triterpenoid saponins, bodiniosides M (1) and N (2), along with three known saponins, oblonganosides I (3), pseudobuxussaponin B (4) and bodinioside A (5), were isolated from the aerial parts of Elsholtzia bodinieri. The structures of compounds 1 and 2 were characterized by spectroscopic data as well as acid hydrolysis and GC analysis as 3-O-β-D-xylopyranosyl-19α-hydroxy-23-acetoxy-urs-12(13)-en-28-oic acid 28-O-α-L-rhamnopyranosyl-(1-2)-β-D-glucopyranoside and 3-O-β-D-glucopyranosyl-2α,19α-dihydroxy-urs-12(13)-en-28,20β-lactone. Compounds 1 and 5 exhibited potent anti-HCV activities in vitro with a selective index of 6.53 and 4.41, respectively.

Full Text

Duke Authors

Cited Authors

  • Zhong, J-D; Zhao, X-W; Chen, X-Q; Li, H-M; Chen, C-H; Xia, X-S; Li, R-T

Published Date

  • June 2016

Published In

Volume / Issue

  • 39 / 6

Start / End Page

  • 771 - 777

PubMed ID

  • 27138284

International Standard Serial Number (ISSN)

  • 0253-6269

Digital Object Identifier (DOI)

  • 10.1007/s12272-016-0750-8

Language

  • eng