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Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials.

Publication ,  Journal Article
Weber, DJ; Rutala, WA; Anderson, DJ; Chen, LF; Sickbert-Bennett, EE; Boyce, JM
Published in: Am J Infect Control
May 2, 2016

Over the last decade, substantial scientific evidence has accumulated that indicates contamination of environmental surfaces in hospital rooms plays an important role in the transmission of key health care-associated pathogens (eg, methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, Clostridium difficile, Acinetobacter spp). For example, a patient admitted to a room previously occupied by a patient colonized or infected with one of these pathogens has a higher risk for acquiring one of these pathogens than a patient admitted to a room whose previous occupant was not colonized or infected. This risk is not surprising because multiple studies have demonstrated that surfaces in hospital rooms are poorly cleaned during terminal cleaning. To reduce surface contamination after terminal cleaning, no touch methods of room disinfection have been developed. This article will review the no touch methods, ultraviolet light devices, and hydrogen peroxide systems, with a focus on clinical trials which have used patient colonization or infection as an outcome. Multiple studies have demonstrated that ultraviolet light devices and hydrogen peroxide systems have been shown to inactivate microbes experimentally plated on carrier materials and placed in hospital rooms and to decontaminate surfaces in hospital rooms naturally contaminated with multidrug-resistant pathogens. A growing number of clinical studies have demonstrated that ultraviolet devices and hydrogen peroxide systems when used for terminal disinfection can reduce colonization or health care-associated infections in patients admitted to these hospital rooms.

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Published In

Am J Infect Control

DOI

EISSN

1527-3296

Publication Date

May 2, 2016

Volume

44

Issue

5 Suppl

Start / End Page

e77 / e84

Location

United States

Related Subject Headings

  • Ultraviolet Rays
  • Patients' Rooms
  • Hydrogen Peroxide
  • Humans
  • Epidemiology
  • Environmental Microbiology
  • Decontamination
  • Anti-Infective Agents, Local
  • 4206 Public health
  • 4202 Epidemiology
 

Citation

APA
Chicago
ICMJE
MLA
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Weber, D. J., Rutala, W. A., Anderson, D. J., Chen, L. F., Sickbert-Bennett, E. E., & Boyce, J. M. (2016). Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials. Am J Infect Control, 44(5 Suppl), e77–e84. https://doi.org/10.1016/j.ajic.2015.11.015
Weber, David J., William A. Rutala, Deverick J. Anderson, Luke F. Chen, Emily E. Sickbert-Bennett, and John M. Boyce. “Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials.Am J Infect Control 44, no. 5 Suppl (May 2, 2016): e77–84. https://doi.org/10.1016/j.ajic.2015.11.015.
Weber DJ, Rutala WA, Anderson DJ, Chen LF, Sickbert-Bennett EE, Boyce JM. Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials. Am J Infect Control. 2016 May 2;44(5 Suppl):e77–84.
Weber, David J., et al. “Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials.Am J Infect Control, vol. 44, no. 5 Suppl, May 2016, pp. e77–84. Pubmed, doi:10.1016/j.ajic.2015.11.015.
Weber DJ, Rutala WA, Anderson DJ, Chen LF, Sickbert-Bennett EE, Boyce JM. Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials. Am J Infect Control. 2016 May 2;44(5 Suppl):e77–e84.
Journal cover image

Published In

Am J Infect Control

DOI

EISSN

1527-3296

Publication Date

May 2, 2016

Volume

44

Issue

5 Suppl

Start / End Page

e77 / e84

Location

United States

Related Subject Headings

  • Ultraviolet Rays
  • Patients' Rooms
  • Hydrogen Peroxide
  • Humans
  • Epidemiology
  • Environmental Microbiology
  • Decontamination
  • Anti-Infective Agents, Local
  • 4206 Public health
  • 4202 Epidemiology